Probiotics for the prevention of Clostridium difficile.
نویسندگان
چکیده
Bottom line Probiotics reduce the incidence of CDAD in patients taking antibiotics, with a number needed to treat (NNT) of 26. However, in a recent, high-quality, publicly funded study, probiotics were not beneficial in elderly inpatients. The influence of funding on study results, as well as the ideal product, duration of therapy, and safety of probiotics (particularly in immunocompromised patients), are unknown.
منابع مشابه
Probiotics for the Primary and Secondary Prevention of C. difficile Infections: A Meta-analysis and Systematic Review.
Clostridium difficile infections are a global clinical concern and are one of the leading causes of nosocomial outbreaks. Preventing these infections has benefited from multidisciplinary infection control strategies and new antibiotics, but the problem persists. Probiotics are effective in preventing antibiotic-associated diarrhea and may also be a beneficial strategy for C. difficile infection...
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Despite advances in the diagnosis and treatment of Clostridium difficile infection (CDI) and prevention efforts to reduce the spread of C. difficile, CDI remains a significant challenge to healthcare systems worldwide. Further advances in prevention of CDI may need to focus on those who continue to be exposed to the organism and who are susceptible. Interventions directed toward this susceptibl...
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Clostridium difficile is a spore-forming Gram-positive anaerobic bacillus, and is the leading cause of nosocomial diarrhea and colitis in the industrialized world. The incidence and mortality rates of C. difficile infection (CDI) have increased dramatically in the past decade. CDI is difficult to treat as antibiotic options are limited. Moreover, 15-35% of patients infected with C. difficile re...
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ورودعنوان ژورنال:
- Canadian family physician Medecin de famille canadien
دوره 59 9 شماره
صفحات -
تاریخ انتشار 2013